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KMID : 0378019730160090043
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New Medical Journal
1973 Volume.16 No. 9 p.43 ~ p.47
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Growth of Russian Spring-Summer Encephalitis Virus in Established Lines of Mosquito Cells
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李淵台/Lee, Yun-Tai
金敬淑/李潤日/金明淑/李種訓/Kim, Kyung-Sook/Lee, Yoon-Il/Kim, Myoung-Suk/Lee, Chong-Hoon
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Abstract
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Growth of Russian spring-summer encephalitis virus in established line of mosquito (Sigh´s Aedes albopictus) cells was studied by infectivity ´ titration of mouse lethal doses and observation of morphological changes on the infected cell monolayers.
The cell line could support the multiplication of Russian spring summer encephalitis virus. The maximum virus titer of 10´´0 mice LD50 was reached in 3 days after virus inoculation. Cytopathic effect was found on the whole monolayer from second post infective day and large round spherical cell aggregates were observed theereafter.
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KEYWORD
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